Chemo and Side-Effects

Fever and Diarrhea

Yesterday as I was posting the blog, I was just fine.  Yet, after then, I started feeling chilly and at night in a Bible study, I was shivering even with a jacket and blanket on me.  Surely enough when I checked the fever after I got home, I had 100F.  Taking Tylenol again, I slept more than 12 hours, and then this morning, thankfully the fever was gone.

After lunch, however, now I  had diarrhea.  Although I knew diarrhea was one of common side effects of Perjeta, I had Sushi!  This is a lesson that raw fish is not compatible with Perjeta.

While I was on Tykerb, diarrhea was one of the major adverse side effects but I could control by anti-diarrhea medicine.  I hope I can control this time as well though I must take anti-diarrhea medicine with me to Israel.

I have 20 more days till our Israel trip.  I have to do my best to bring my body into a good condition.



Seeking Miraculous Healing Medicine and Pool

Thought Watching the Olympics

“ The Olympics are like a circus,” said George.

Indeed, watching snowboarding, which flies like a cannon, or artistic but also acrobatic figure skating, I feel like they were astonishing super humans.

A long time ago, when I saw a figure skate medalist, Janet Lynn, who had a blond bob haircut, I was so fascinated by her skating that I determined to learn figure skating, and in college, I joined a figure skating club.    I did not excel, but I still have the white made-to-order skate shoes.

Watching the elegant skaters, I feel a strong nudge to stand on the ice right away and to imitate that graceful skating.  Yet, the reality is that my legs are so stiff that I cannot even squat without holding bars and I am stretching and bending my legs in front of the T.V..

I wonder maybe the Olympians are not only training hard but also taking some drugs to make their bodies strong and flexible.  If there is such a drug, I want it!

Should I Google it?

 Miraculous Healing Pool, Bethesda

In Jesus’ era, in Jerusalem there was a pool called Bethesda, where the crippled, blind, or sick could be completely healed if they got into it.  It was excavated in the 1950’s and I am going to visit there.

Jesus asked a crippled man, who was laying there for many years wishing to jump into the pool, if he wanted to be healed.  As the man said, “Yes,” Jesus commanded him to stand up and walk, and he did.

At Bethesda, remembering this miracle, if I pray for healing, my cancer may be gone and this stiff body may be healed completely.

Counting the days to the Israel trip, I am expanding my imagination.

The pool of Bethesda

The site of Bethesda


New Challenge: Peripheral Neuropathy

“Some people may experience temporary numbness, tingling, and pricking sensations (paresthesia), sensitivity to touch, or muscle weakness. Others may suffer more extreme symptoms, including burning pain (especially at night), muscle wasting, paralysis, or organ or gland dysfunction. People may become unable to digest food easily, maintain safe levels of blood pressure, sweat normally, or experience normal sexual function. In the most extreme cases, breathing may become difficult or organ failure may occur.”

This article included all my symptoms which have been concerning me more and more recently.  Not only numbness and tingling, but also cramps, the weakened legs, stiffness which now I experience even with fingers, and shortness of breath during the night—all of them must have happened because of peripheral neuropathy!

Two years ago I quit taxol that erased the metastasized cancer in the mediastinal lymph nodes to prevent the symptom of peripheral neuropathy from getting worse. Yet the miracle drug, T-DM1, might have the same side effect.  My symptoms are getting severer than last year.

It has been  7 weeks since I changed from T-DM1 to Perjeta+ Herceptin, but the symptoms have not improved yet.  I wonder if Perjeta, the drug approved two years ago,  may also affect the peripheral nerves.  Peripheral neuropathy is irreversible according to many websites.  Even if I can beat cancer, I may wind up to be in wheelchair.

That doesn’t sound good.  I have to do something.

Need to Be Re-Charged

I thought I caught a cold.  Yet, I haven’t felt better even after a week.  I feel chilly and sluggish; I easily run out energy, and am laying on the couch most of the time doing nothing.

Is this a side effect?  I have had only two infusions of Parjeta, and it has been two weeks since the 2nd infusion.  This new drug is an antibody drug like Herceptin, so  the side effects should be mild.  Yet, this reminds me the beginning of  my battle of cancer when the chemo was very hard on me.  I can’t believe that I went to Israel and  handled the hard schedule of the trip for 10 days!

I want to visit my mom in Japan again in April if I can, but as of now I don’t know if I can make it even to LAX.

I should have a blood test to find out if something is wrong with me.

I need to be re-charged!


Strategies for Peripheral Neuropathy

My energy level was so low and I was praying for re-charging last week, but finally God granted the prayer!  Now I feel like I can make it not only to LAX but to Japan.  🙂

I thought I was wasting  precious time, but I guess it is good to rest and sleep as much as we want when we don’t feel well – without feeling guilty.

 Fighting Back with  the Peripheral Neuropathy

 Once I got energy back, I am ready to fight back with the peripheral neuropathy.

My strategies are:

1)   Chinese medicine:Gosha-Jinkigan

This medicine is widely used together with chemo, which causes peripheral neuropathy, as the prevention in Japan.  I was trying it also for a few months but I stopped it as I experienced itchiness.  Yet it seemed like the cause of the itch was not the Chinese medicine but a Japanese supplement I was taking simultaneously.  For two weeks since I resumed the medicine, I haven’t had the itch and the muscle ache and stiffness have been improved.

2)   Exercise

My doctor has recommended it, and though the cough and bloody nose made it difficult to continually swim, I decided to go back to the gym to stretch and work on the muscles.

3)   Tai Chi

I have been interested in Tai chi since I heard that the deep breathing technique helps the circulation of blood and good for cancer, but finally my friend invited me and now I am in the class.

4)   Frankincense and Myrrh

The Bible says three wise men gave Jesus these as their gifts with gold when He was born.   When I decided to go to Israel, my cancer friend asked me to get them for her.  She said these oils works as a pain medicine.  As I Googled it, she was right.  I learned the oil has been used for pains since  ancient times.  More surprisingly I found out that Amazon sells the oil for neuropathy, and many other sites even said that this oil helps glaucoma and peripheral vision!   Then why not try it?

It has an awful smell and is greasy, but if it works, this is a great discovery!

5)   Most importantly, of cause,  Prayer

“  Paul wrote, ‘ I can do all things through Christ who strengthens me.’” –Philippians 4:13

With the Bible, I was greatly encouraged!  🙂


Three More Surprises

One month after the latest CT confirmed the 3rd recurrence of cancer, finally I started the 8th regimen adding Taxol this Monday.

The peripheral neuropathy has worsened even after I quit Taxol for the last two years, and  now it has been even interrupting my sleep by causing cramps, spasms, burning, and numbness  since last June, when I  held off Goshajinkigan (a Chinese herb medicine) due to a concern of the side effects on the liver.

I chose Taxol again, hoping it will shrink cancer once more, but my peripheral neuropathy is already pretty serious.   After I passed the liver biopsy,  I have been preoccupied with it.

Taking many tablets of supplements which are said good for peripheral neuropathy according to my research, I did my best to protect myself from the side effects of Taxol.  Yet, the cramps and spasms happened mercilessly over and over the night before the chemo, and even being in the chemo chair. I felt the sensation of cramping and was afraid of it tormenting me anytime.

As the five hour chemo was done, not only my legs but the whole body was so heavy that I barely walked down the stairs.

At night, however, something unexpected happened.  There were almost neither cramps nor spasms, and the next day, I felt my legs were so light that I could even run as if I had never had troubles with my legs!

What in the world happened?

I had a steroid with chemo.  Maybe it helped the neuropathy.

I couldn’t believe myself who felt better than being before the chemo!

Then at night an email came from the GI doctor regarding the varices.

“Since the liver biopsy was negative for cirrhosis, …the varices are either an over-call or …the cause is unknown. ….I think that the varices are unlikely to cause any problems to you over the long term. ”

Yay! Though I passed the biopsy, I was still wondering what to do with the varices. Yet this concern is cleared out, too!

I heard about the Sudanese Christian woman, who sentenced the death and 100 flogs penalty was rescued, too.

I give all credits to prayers.  How powerful the prayers are, and for our Heavenly Father, nothing is impossible!

I am so grateful.


Questions For A Neurologist

The miraculous relief from the peripheral neuropathy lasted only for a short time, and tingling, numbness, and burning sensations have come back. Because this is just the beginning of the treatment with Taxol and I’d like to be on this med at least 6 months, I visited a neurologist and asked many questions.

Q1: Are there ways to prevent or cure peripheral neuropathy?

A: The prevention or cure is very difficult.  What we can do mostly is to reduce the pain and discomfort.

( It is so disappointing and I don’t want to believe it. ;-( )

Q2.  After the first infusion, surprisingly the troubles in the legs almost disappeared.  Is it because of the steroid?

A:  It could be.  But if you use the steroid for a long time, it may cause diabetes.

( Oh yes.  Two years ago I stopped the steroid because my sugar lever elevated. )

Q3. I found out there are breast cancer patients who use vitamin B6 shots the day before chemo and on the day of chemo.  What do you think about the shot?

A: Too little vitamin B6 is a problem but too much vitamin B6 could worsen peripheral neuropathy, too, though vitamin B12 is fine.

(Wow!  I was trying to take many pills of Vitamin B6!)

Q4.I read some articles that supported high doses (21mg) of Melatonin (a medicine for insomnia)prevented peripheral neuropathy. How about this?

A: 21mg is too much.  Take 3mg per day.

(Hmm….I am afraid that 3mg is not enough….)

Q5. How about Alpha-Lipoic Acid?

A:  This may work.  Try to take 300mg x2/day.

(Thank you!  Finally there is something possibly effective.)

Q6.  How about Acetyl-L-Carnitine or Glutamine?

A:  I think Alpha-Lipoic Acid is better, but have no objection for them.

(I found the name of Alpha-Lipoic Acid on the front page of some cancer magazine issued in this month, but I also read this medicine may afftect on thyroid.  I already have hypothyroid, so I am going to try Glutamine.)


I was told to see him again in four months.  Hopefully something will work and I can bring some good news to him. 🙂


Acupuncture: Peculiar But May Work

The neurologist  said medicine was the first line for peripheral neuropathy and if it doesn’t work, he can refer to an acupuncturist (and I can use the insurance.)  I pondered about Gabapentin, an anti-depression med the neurologist recommended, reading the description and some websites. It could cause multiple serious side effects, and it didn’t appeal to me enough to choose it.

Two weeks ago was the worst – not being able to sleep because of numbness, tingling, burning, cramps, and spasms in legs. Yet last week was better. Perhaps it was because of lots of supplements as well as acupuncture I’ve experimented with. I emailed the neurologist that I want to continue what I am taking including acupuncture instead of taking the anti-depression drug for peripheral neuropathy as of now.

My first experience of acupuncture was a little interesting.

The old white-haired man coming out from the back of an old plain office escorted me to his desk and asked what was the problem.

While I was answering  him in English, he was writing a couple lines in Chinese on a line paper.

Then he said, “One session is $40. Let’s start.”

Because I was not sure if he really understood my problem, I asked him,

“Before we start, would you please explain what you will do and how it works?”

“Yeah, yeah, yeah, come this way.”

He took me to a booth, which had a bed.

I asked him again to explain what he would do and how it works.

“Yeah, yeah, yeah, I put needles here, here, and here (pointing some spots on his body.) Change to the gown.”

I was not content with his answer and got nervous, but changed into the gown anyway.

As he came into the booth, I asked him the 3rd time.

“ This is the first time for me and I don’t know much about acupuncture.  Until you tell me how acupuncture works for me – if it’s like Tylenol working only for short time or is able to cure – I won’t pay you.”

Then finally a young guy came in from the back of the office, and explained to me in good English:

In a body there is a circulation of energy called ”Chi”.  If this circulation is blocked with some reason, a problem happens.  Acupuncture stimulates spots to bring the circulation back to normal.  It is curable and safe.”

O.K.  Finally I was convinced and laid down on the bed.  The doctor poked about 8-inch needles on my forehead, left and right shoulders, and calves.  They didn’t hurt except the needle near the left ankle, but as I said it hurt, he changed the spot and then I was o.k. I was still on the bed for about thirty minutes.

Right after the acupuncture, I felt sluggish just like after chemo, but by the night, I felt my body was so right with little tingling more than ever!

The young guy told me to visit twice a week and continue for a few weeks to see the better result.

It was peculiar,but it may work!

Excruciating Pain from Infection

Since last Friday, after dinner, around the teeth I had implanted 5 years ago it has been hurting. The pain became so intense spreading even to my head and neck  that it was almost unbearable.

Holding onto a pain med, I finally visited a dentist.

” There aren’t nerves under the implants any more, so this is an infection.  Do you know what your white cell counts are?”

The dentist asked.

I downloaded the lab result through the iPad.  The numbers have decreased since I started Taxol.  If we don’t have enough white cells, we get easily infected, and infections could kill us.

“This is about the bottom line of the normal range.  You have to be careful,” said the dentist.  Receiving prescriptions of an antibiotic with a pain medicine, I was relived anticipating I would be OK soon.

I am so thankful that I live in the modern world where antibiotics are available.  Also, I am thankful that the dentist took me in immediately, while (I don’t know if I should blame Obama Care or not) it is getting harder and harder to make a prompt appointment now days.

Infection Canceled Chemo Infusion

Calling for a New Medicine

Two tarantulas, big hairy poisonous spiders, jumped on me; one  ripped off my finger, and another bit my head.


I screamed and then George woke me up.

It was a dream.  My infected gum hurt so bad that I had a nightmare- I guess.

Although I was taking the antibiotic  for three days, it didn’t seem to be working.  I needed pain pills more than the direction said.

Last Saturday,the next day after I had a bad dream,  I called the dentist asking for a new antibiotic.  Yet he told me to finish the first antibiotic and let him know how I would be on Monday.

Hanging up the phone, I pondered if I could wait until Monday, or if it’s ok to leave the infection with ineffective medicine.

 No.  I don’t think so.  If this is an infection, probably a Kaiser doctor can prescribe a different antibiotic.

I called Kaiser and then a nurse told me to go to Urgent Care.

Once I started the new antibiotic, the pain went away immediately.  This time it must be working.


Unexpected Postpone

However, an unexpected thing happened at the chemo ward on Monday.   I was told that I had to postpone my chemo infusion until next Monday.

“If you have an infection and add chemo, the infection would get worse.  You don’t want that,” said a nurse.

 If I miss chemo, what would happen to cancer?

That was my reaction.  Yet I have had three drugs.  Hopefully canceling one drug one time won’t be a big deal.

Right now fixing the infection completely as soon as possible is more important.   Meanwhile I hope I can have good night sleeps without nightmare!

I’m Desperate for Good Sleep

Trouble sleeping has been a long-term issue for me, but it has worsened as the peripheral neuropathy has gotten  worse.

It is difficult to fall asleep at first, and then  I wake up in the middle of a night and have a hard time to go back to sleep.
Often it is because of numbness and burning discomforts of my legs, sometimes because of shortness of breath like an elephant was sitting on my chest, sensations to go to the bathroom, hot flashes, and even George’s cough or tossing.
As I struggle to sleep, turning over side to side, now I wake George up.
If I hear a cuckoo clock in the living room every 30 minutes for a few hours, with frustration, I get up.
Last night, too, I stayed up until around 5am.  Finally I got sleepy and went back to bed, but since I had a doctor appointment at 8:30am, I slept only 2 hours.
Without good night sleep, I can’t focus, get grouchy, inpatient, irritable, unkind, and overwhelmed easily.
Probably my immune system also gets weak, and maybe that’s why I was infected.
As I complained about this insomnia to the doctor, she suggested to quit Taxol as soon as possible.
No, no, no!
I am betting on taxol to shrink cancer, and I want to be on it as long as possible. Yet, I should wait to discuss about it until I see the result of the next CT.  Hope I can sleep better tonight.

Watching Glucose Level

A good glucose (sugar) level in the blood is between 70-99, according to Kaiser. Yet my glucose level has been elevating more than this range since I started a steroid along with Taxol.

Last week as it hit 125, I experienced thirst and was so close to the bathroom.  If you are diabetic, the level goes up more than 200.  Though my case was not serious like that yet,I got nervous and changed my diet immediately because my father was diabetic, and most importantly diabetes causes peripheral neuropathy, I read.

I avoided not only sweets, but also white rice and bread.  Then immediately the level dropped from 125 to 99.  Wow!  Starch like white rice and bread, affects the glucose level greatly.

However, if I go by a sweet section at a supermarket, the temptation becomes great.  As I gave in, the level went up high and then I tried hard to limit myself next day.  The glucose level has been up and down between 125 and 97.

If I keep injecting the steroid every week, it must become more difficult to control by diet.  Also, two years ago when I stopped the steroid, I didn’t have any problem. Two thoughts made me email the oncologist, who told me I should not go off the steroid, asking again to reduce the dose of the steroid, and she finally accepted my request.

After the dose was cut into a half, this morning, the glucose level was 89, which is ideal.

I was relieved so I ate a piece of blueberry pie!

Kathy, watch out!  You should continue to keep the good eating habit you just learned!

Is Taxol Working?

I started taxol on 6/30 and I am now on the 3rd cycle.  Yet I still have hair which had been shaved to about half an inch long.
Two years ago when I first used Taxol, I was on it three weeks followed by a week off.  This time as I was following the schedule the hospital gave me, I noticed I haven’t had any week off.
The doctor answered my question saying that I could be on taxol weekly or with a week off.  “What would you like?” She asked.  Of course I want a week off because I am concerned peripheral neuropathy very much.
So the cycle was fixed, but until September I will have been on taxol for 11 weeks in raw except one week when the infusion was canceled due to the infection.
In spite of that, I still have hair.  Why is it?
Is taxol not working?  Is it because I’ve been taking so many supplements? Or both; high doses of supplements is interfering the work of taxol?
How about peripheral neuropathy?  I was so afraid that it would become worse once I start taxol.  Though tingling, numbness,  burning, etc, all the symptoms of peripheral neuropathy are still the main issue,  they also seem not getting worse yet.  Actually I’ve been able to sleep a little better since I restarted the Chinese herb medicine.
The new regimen should work well because this regimen is one of the newest blockbusters and I am taking taxol more often than two years ago adding even vitamin D.  If not, I will be very disappointed.
Thy will be done!

Heat and Cramps Discourage Exercise

Our house doesn’t have any AC.  We only have two fans.  Usually even if downtown LA has over 90 F, with the breeze from the ocean here in Torrance, I seldom feel hot or sweaty.  However the last  few days, even in Torrance, the temperatures hit 99F and without AC it is as if I were in an oven.  I don’t feel like doing anything and just have long naps.

During the naps and even the nights’ sleeps, the cramps have attacked over and over and woke me up.

I went to a Tai-chi class on Wednesday, and the cramps started raiding from that night.

I thought the Chinese herb medicine was helpful for cramps, but not always; the cramps have attacked me drawing waves.  Maybe the high-heels sometimes I wear contribute to them, too.

Because lots of sites say exercise is good to prevent cramps, I am trying Tai-Chi and at Kaiser, I choose stairs instead of an elevator to get to the 3rd floor, where the oncology department is,  but as I get to the 3rd floor, my legs feel so heavy and I am out of breath.

I am afraid that my muscles are so weak and this is a symptom of peripheral neuropathy, which has been damaging my nerve system continually.

The heat and the cramps discourage me to do exercise.  Aah, if Pepper were with me, I wouldn’t wonder but walk with her and that would be the right exercise for me.  I miss her!

The 5th Birthday From the Diagnose

It is 3:30 am. I am up because I can’t sleep.
From yesterday George and I are at a ranch in Santa Ynez, known for its wineries. This is my birthday family trip and the kids are coming today. I will be 60 on the 21st and this is also the 5th birthday from the diagnose of breast cancer in 2010.
Being surrounded by rural scenery of mountains, vineyards, green farms, and livestocks such as hoses, caws, sheep, and goats, I have enjoyed this beautiful, spacious, peaceful place.
In spite of that, at night the leg cramps continually attack me and then, shortness of breath, and spasms interrupt my sleep.
I took all kinds of medicines and supplements, but none of them helped.
I woke up and am thinking that I am no longer young; the battling against cancer or the side effects are getting tougher.
Yet, if I look back, while I was always concerned with the same, gratefully I have been able to manage the side effects and survive so far.
I didn’t expect that, and then I feel like this 5th birthday is a milestone. I could do that because not only George and the kids, but also my families in both Japan and the U.S., as well as many friends have supported me and most importantly God has been with me.
Sleepless nights may continue and the concerns are endless. However, God was, is, and will never leave me!
Now I am encouraged and my legs feel better. I am going back to bed hoping to be able to sleep now.
Lampoc Winary

View from the ranch

The view from the ranch

Passing Out in Bathroom

My cough was getting bad again this week.
Yesterday it was constant, I had no appetite, and ran a fever, too.

I don’t remember what time it was, but shortly after I took Robitussin – because the constant cough didn’t allow me to sleep – I started feeling nauseous and the nausea was getting stronger and stronger rapidly. Feeling urgency, I stood up to go to the bathroom, but just a few steps later, all strength slipped out from my legs and I fell on the floor. I couldn’t stand up so I crawled to the bathroom.

I was totally groggy and felt like a cold sweat was breaking out from every part of my body. I remember that. Then next moment, George was next to me stroking my back and said, “ Are you OK?” He heard me moaning and found me crouching down on the floor in the bathroom, though I don’t remember.

Going to the bathroom helped me and after then I could sleep well. Now I have less cough, no fever, and an appetite also came back.

I will go to a lab tomorrow, so if something is wrong with me, the result may show it. I am glad now I feel better and so thankful for George who took good care of me. I don’t know what I would do without him. Gratitude.

Finally Found Comfy Shoes for Hand-Foot Syndrome

Just less than two weeks after I started Xeloda, I’ve already experienced a side effect, blisters on my sole.  It was mere blisters, but on my sole it hurt so much that I barely walked.

After holding-off therapy for two weeks due to the oral surgery, I resumed it as the 2nd cycle last week.  Wishing to avoid the blisters this time, I was hunting for comfy shoes for days, and finally I found them.

1)   The shoes have to be flat or low heel.

2)   They have good cushions under the feet.

3)   The front is open so the toes won’t touch the shoes.

4)   I can wear them even with socks or dressing.

5)   I can wear them for nice occasions, too.

Those were the conditions of the shoes and here are the shoes I found.

They were made by Cobb Hill ($100).  All the bands have velcro so I can adjust the size as I wear socks or have dressing on the feet.  They are light, comfortable, steady, and look feminine.  Now I should be able to walk without worrying about blisters and I love them!

What Chemo Did to Teeth

I went back to the dentist for a root canal this time.
Shooting the anesthesia, the treatment began, but shortly after the dentist asked me,

“How long will you have chemo?”

I answered, “ No end. My cancer is metastatic, so I have to continue for the rest of my life.”

Then he and his wife as his assistant, who were looking at inside of my mouth together, conversed in Chinese. (Yes. The dentist is Chinese-American.)

As he continued his work a little more, his wife turned off the light upon me, and the treatment, which was supposed to be for two hours, was done in less than an hour.

“Instead of a root canal, he put in a filling. He will explain the reason,” said the wife.

Sitting at front of my x-ray images, he started:

“ The reason why I asked about chemo was, if you continue on chemo, your immune system becomes weak, and it will have effects on the root canal,”

“Because you said it didn’t hurt, I put in a filling. If it starts hurting, you have to have the root canal, but let’s see.”

According to the dentist, the bone cell has a cycle; birth to death in 3-6 months. Once an old cell dies, it is cleaned up and a new cell is born. Yet in my case he is concerned that this cycle is affected by the low immune system and the regeneration of the bone process is slow.

“So, you mean it’s a side effect?” I asked.

“ Maybe,” he said.

“Then, the same problem may happen again?”

“ Yes.”

Really? Oh my God!

My blood cell count has been in the normal range except during the first regimen when I had to be admitted to the hospital to boost up the number. However, as I have been constantly on chemo for the last five years, the oncologist also told me that my immune system was probably weak now.

After listening to the dentist, I thought;

1) I am longing for a cancer vaccine, but the longer I wait being on chemo, perhaps the less it will be effective because the vaccine relies on the immune system.

2) The amount of the radiation I have received from CT scans, which I have taken every 2-3 months for the last five years must be enormous and may have affected my body, too.

3) Cancer survivors live longer compared with 10 years ago, but the reality is that the longer the battle becomes, the more it becomes complicated and difficult.

3) I should strengthen my immune system.

So, I ordered AHCC, a supplement.

AHCC May Enhance Immune System

AHCC stands for Active Hexose Correlated Compound which is a chemical isolated from the Shiitake mushroom.

I encountered encouraging information that this supplement, can protect the immune system from side effects of chemo, especially from a low white cell count, Neutropenia.

It was last year when I received a box of the supplement, AHCC from my cousin in Japan. She said, “ When I feel coming down with something, I take one package of this, and then I get back energy.”

As she said, as I have tried AHCC for the morning when I woke up with sore throat or fatigue, it worked. Then, since the day I was told by the dentist that my immune system might be weak because of chemo, I have taken this supplement 1g everyday as the label of the bottle suggested.

However I was surprised reading a site, in which multiple terminal pancreas cancer families said AHCC suppressed the side-effects and the patients recovered from poor appetite, fatigue, fever, etc, and even stopped cancer progression when they took it along with their chemo.

I am not sure how reliable those comments are, but also found quite a few articles supporting the effectiveness of AHCC on the immune system with evidence.
This supplement may help preventing not only neutropenia, but also rising liver enzymes.

For the next regimen, I’d like to try T-DM1, which two year ago I had to go off due to the rising liver enzymes. Being encouraged by this information, I also would like to try AHCC with 3g per day, which was the recommended dose for cancer patients.

Going Back to T-DM1

Monday, receiving the approval from my oncologist, I started on T-DM1( Kadcyla) again today.

I have used it in 2013, a little after the FDA had approved this dream med.
As the FDA approved it for metastatic breast cancer, the oncologist first questioned about the use of it for me, who was in remission that time, but at the end she accepted my request, and I was on it for 8 months extending the remission until Dr. Slamon, who invented Herceptin, told me to stop it due to the concern of the side effects, which were the decrease of the platelets numbers and the increase of the liver enzyme level.

However, He told me that I would be able to use it again in future because the reason of stopping was not the progression of disease but the side-effects.

So, I decided to try it again as the 2nd round, though usually the 2nd round is not effective like the first time.

I am wondering if I add one more drug to T-DM1, if it will help the effectiveness. I know a recent clinical trial of T-DM1 and Perjeta showed nothing better than T-DM1 alone, and also have a concern that Perjeta may not be effective for my cancer any way. Despite those concerns, I still hope for some surprise. Or I wonder about adding Abraxane, which is like a brother of Taxol, the med that brought me into the remission, though it will probably worsen the peripheral neuropathy I’ve been suffering since I was on it.

Anyway I will save those questions for the consultation with Dr. Slamon next month. There are quite a few women who have been in remission for 2-3 years with T-DM1 controlling their side effects. I pray that this med will work again for me like those women and give me more time on the earth.