Going Back to T-DM1

Monday, receiving the approval from my oncologist, I started on T-DM1( Kadcyla) again today.

I have used it in 2013, a little after the FDA had approved this dream med.
As the FDA approved it for metastatic breast cancer, the oncologist first questioned about the use of it for me, who was in remission that time, but at the end she accepted my request, and I was on it for 8 months extending the remission until Dr. Slamon, who invented Herceptin, told me to stop it due to the concern of the side effects, which were the decrease of the platelets numbers and the increase of the liver enzyme level.

However, He told me that I would be able to use it again in future because the reason of stopping was not the progression of disease but the side-effects.

So, I decided to try it again as the 2nd round, though usually the 2nd round is not effective like the first time.

I am wondering if I add one more drug to T-DM1, if it will help the effectiveness. I know a recent clinical trial of T-DM1 and Perjeta showed nothing better than T-DM1 alone, and also have a concern that Perjeta may not be effective for my cancer any way. Despite those concerns, I still hope for some surprise. Or I wonder about adding Abraxane, which is like a brother of Taxol, the med that brought me into the remission, though it will probably worsen the peripheral neuropathy I’ve been suffering since I was on it.

Anyway I will save those questions for the consultation with Dr. Slamon next month. There are quite a few women who have been in remission for 2-3 years with T-DM1 controlling their side effects. I pray that this med will work again for me like those women and give me more time on the earth.

Headache Is Gone

The headache, which bothered me everyday for the last whole week stopped all of sudden yesterday. My right ear was also throbbing and ringing, but it stopped as well.

Yesterday was a chemo day. As I woke up with a headache, I took Tylenol before I left for the hospital, and since then all pains and aches have been gone.

If I think that both aches from the head and the ear stopped together, probably they were related. Maybe Tylenol helped temporary but the real helper was the chemo, Kadcyla (T-DM1). If so, the cause could be cancer.

Is Kadcyla so effective that it instantly suppresses cancer?

If it’s so that is great, but if cancer has spread into the brain, that is serious. I am thankful that I am pain free now, but not sure if this means good news or not.

I can’t wait for a brain MRI.

Setback or Progression

I was so frustrated with the slow recovery from pneumonia. Last week once I resumed the infusion and oral chemo, I was admitted to the hospital again because of the shortness of breath.
After the discharge, I thought finally I was getting better Sunday afternoon and Monday. Yet from Tuesday I felt weak again and since Thursday night I have had fever.

On Wednesday a family doctor, who ordered an X-ray again, told me I had new pneumonia in a different spot. Then today as I went to the Urgent Care, a different doctor said that the radiologist, who read the X-ray, didn’t mention it was pneumonia. So it could be a viral infection or something else.
The doctor ordered a blood test. Though I haven’t talked about the result with him yet, the numbers of the blood test I received through email were all in the normal range. At least for me there appears no sign of infections.

I have read if cancer in lungs progresses, it causes pneumonia,fatigue, fever, cough, chest pain, chills, and the shortness of breath, which all I have had in this month.
I haven’t taken a CT scan since last December though my routine is every three months. I now wonder if those all symptoms are the signs of cancer progression. If so, I have to change the regimen quickly. And next questions are how I know if this is a setback or progression and if it’s the progression, when and what to change the regimen.
Yet instead of imagining this or that by myself, I should listen to the doctor’s diagnosis, which I might have to wait until Monday.